Veins is funny. It's also very, very sad.
It tells the story of one dude and his inability to connect with the world. In the beginning you empathize, but by the end you just want someone to explain to him what's really going on, and why these things are happening to him. This is the kind of book that can be quite depressing if you're feeling just a little bit down yourself. Approached from your happy place, it has some nicely humorous passages. I think my favorite is the passage printed on the back cover:
"It's like you're born, and they put eggs and index cards and fish in a blender, and you have to drink it. Every sip is worse, but you have to keep going every day. The last sip is horrible, and then the glass is empty, and life's over."
Also FYI, Drew is the author of ToothpasteForDinner, which was my very first internet web comic discovery.